Although the biological function of H19 in HCC remains to be elucidated, Nokkeaw et al. suggest that H19 may act as a molecular sponge for miR-107 to promote cyclin-dependent kinase 6 (CDK6) expression and cell cycle progression; this axis may explain the correlation between H19 overexpression and increased cell proliferation in HCC [540]. This evidence concerns the gene H19 and hepatocellular carcinoma.