The forkhead box-containing protein O subfamily1 (FoxO1) showed the strongest positive correlation with MDR1 expression and Cellular tumor antigen TP53 exhibited the strongest negative correlations (Figure 6C); our results showed that the relative expression of inducer FoxO1 was significantly downregulated in the LGG group compared with the ATB group, while the relative expression of inhibitor TP53 was evidently upregulated. This evidence concerns the gene FOXO1 and neoplasm.