PTGS2 and early-onset autosomal dominant Alzheimer disease: Thus, we recommend that advanced studies of this extract be performed in the future to evaluate its biological activities and elucidate its mechanism against Alzheimer’s disease (anti-AChE enzyme), inflammation (anti-COX-1, anti-COX-2, and anti-5-LOX), diabetes mellitus (anti-α-amylase and anti- α-glucosidase), and cancer diseases in rats.