This may be explained by the fact that the LH to FSH ratio in the follicular phase of the cycle is usually higher in women with polycystic ovary syndrome than in their peers without ovarian disease [9], while low ovarian reserve, observed in postmenopausal women, is manifested by a more pronounced increase in FSH than LH [10]. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.