Moreover, a review by Caproni et al. summarized the immunopathogenesis of DH, emphasizing the role of IgA deposits in the skin and the cross-reactivity between epidermal transglutaminase (the autoantigen in DH) and tissue transglutaminase (the autoantigen in celiac disease) [57]. Here, TGM2 is linked to dermatitis herpetiformis, familial.