Non-IgE cell-mediated food allergies pose a greater diagnostic challenge and are categorized into various disorders, including allergic proctocolitis (AP), celiac disease/dermatitis herpetiformis, food protein-induced enteropathy (FPE), Heiner syndrome (pulmonary hemosiderosis), food protein-induced enterocolitis syndrome (FPIES), and cow’s milk (CM) protein-induced iron deficiency anemia [4,5,17]. The gene discussed is IGHE; the disease is Iron deficiency anemia.