The HLA-B*27:05:02 allele is positively associated with enthesitis, dactylitis, and symmetric sacroiliitis, while the HLA-B*08:01:01 and HLA-C*07:01:01 haplotype is associated with joint fusion and deformities, asymmetric sacroiliitis, and dactylitis [11,14]. The gene discussed is HLA-B; the disease is enthesitis.