Preclinical studies indicate that [6]-gingerol effectively inhibits tumor cell proliferation, induces apoptosis, and modulates key oncogenic signaling cascades, including NF-κB, MAPK, AMPK, and AKT/mTOR, while also suppressing JAK/STAT-mediated immune evasion mechanisms [23,24,25,26]. Here, NFKB1 is linked to neoplasm.