Immunohistochemical experiments revealed that after M0-delADP/KD01 treatment, the expression of nuclear division and proliferation-related protein (Ki67) in tumor tissue decreased, while the level of terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) increased, indicating a weakened proliferative ability and increased apoptosis levels in tumor tissue after treatment (Figure 4E,F). The gene discussed is MKI67; the disease is neoplasm.