CHEK2 and melanoma: The authors concluded that individuals with CHEK2*1100delC heterozygosity have a twofold risk of melanoma compared with non-carriers (OR 2.01 (1.03–3.91) in the Danish, 1.42 (0.46–4.31) in Germans, and 1.79 (1.02–3.17) in the Danish and Germans combined) [29].