The reduction in the consumption of foods such as sweets, high-fat red meat, soft drinks, and alcohol, depending on the timing of dietary changes (more than six months ago or within the past six months), was associated with significant changes in parameters including BMI, systolic blood pressure, serum lipid levels, fasting glucose and insulin concentrations, sex hormone-binding globulin, total testosterone, free testosterone, androstenedione, and acne severity. This evidence concerns the gene INS and acne.