Moutal et al. studied CRMP-2 expression and phosphorylation in three human glioblastoma cell lines (GL15, A172, and U87) using cyclin-dependent kinase 5 (Cdk5) and glycogen synthase kinase 3 beta (GSK3β) to elucidate their roles in CRMP-2 regulation. The gene discussed is CDK5; the disease is glioblastoma.