F10 and Paroxysmal atrial fibrillation: Analysis from the ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis In Myocardial Infarction 48) demonstrated 27% and 22% lower all-cause mortality in patients with paroxysmal AF compared to patients with persistent AF and permanent AF, respectively [26].