Regarding physiological PTH levels, one recent study showed in patients with a novel T2DM a negative association between PTH levels and HbA1c at diagnosis of T2DM (β = −1.475, p = 0.003), and a positive association with HOMA-B% (β = 0.090, p = 0.001) [68]. The gene discussed is PTH; the disease is type 2 diabetes mellitus.