Additionally, elevated serum resistin was associated with an increased risk of CHD development in postmenopausal women with T2D, as its rise coincided with elevated inflammatory and endothelial dysfunction markers such as high-sensitivity C-reactive protein (hsCRP), total plasma homocysteine (tHcy), IL-6, and soluble vascular cell adhesion molecule (sVCAM) [26]. This evidence concerns the gene RETN and type 2 diabetes mellitus.