Several mechanisms contributing to sarcopenia have been identified, including the degeneration of α-motor neurons in the spinal cord, the impaired secretion of endogenous growth hormone and insulin-like growth factor-1 (IGF-1), androgen and estrogen deficiencies, insufficient dietary protein intake, the increased expression of catabolic cytokines, and decreased physical activity [5,6]. The gene discussed is IGF1; the disease is sarcopenia.