Hashemzaei et al. [26] proved that quercetin triggers apoptosis in various cancer cell lines, colon carcinoma CT-26 cells, prostate adenocarcinoma LNCaP cells, human prostate PC3 cells, pheochromocytoma PC12 cells, estrogen-receptor-positive breast cancer MCF-7 cells, acute lymphoblastic leukemia MOLT-4 T-cells, human myeloma U266B1 cells, human lymphoid Raji cells, and ovarian cancer CHO cells. The gene discussed is ESR1; the disease is plasma cell myeloma.