CRP and chronic kidney disease: In multivariate logistic regression analysis pertaining to factors associated with PAD, including DM, age, UPCR, CRP, and endocan, we identified that elevated serum levels of endocan (odds ratio [OR]: 1.098; 95% confidence interval [CI]: 1.042–1.157; p = 0.001), advanced age (OR: 1.097; 95% CI: 1.038–1.159; p = 0.001), and the presence of DM (OR: 3.437; 95% CI: 1.053–11.225; p = 0.041) were independent predictors of PAD in individuals with CKD at stages 3 through 5 who are not undergoing dialysis (Table 3).