MTDH and hepatocellular carcinoma: Pro-inflammatory cytokines, such as interleukin-1β (IL1B) and TNFα, and lipopolysaccharide (LPS) induce AEG-1 expression via activating Nuclear factor-kappa B (NF-κB) thereby establishing a link between AEG-1 and chronic inflammatory cancers like HCC [46,47,48].