Multiple tumor-suppressor miRNAs, such as miR-30a-5p, miR-195, miR-302c, miR-375, and miR-497, target AEG-1 so that their downregulation in cancers results in the upregulation of AEG-1 in a post-transcriptional manner [49,50,51,52,53,54]. Here, MTDH is linked to cancer.