Following the methods described in the section on the syngeneic mouse model with radioresistant PCa, Myc-CaP-R was inoculated into the mice, and tumor volumes were evaluated 7 days after the completion of treatment in the four groups (control, 5-ALA alone, IR alone, and 5-ALA + IR; Figure 5c,d). This evidence concerns the gene MYC and posterior cortical atrophy.