Several miRNAs, including miR-20a-5p, miR-92a-3p, and miR-17-5p, have shown greater than 90% sensitivity and specificity for identifying BC, whereas lncRNAs such as UCA1-201, HOX transcript antisense RNA (HOTAIR), and metastasis associated lung adenocarcinoma transcript 1 (MALAT1) have comparable diagnostic accuracy. The gene discussed is HOTAIR; the disease is breast cancer.