CITED2 and acute lymphoblastic leukemia: Although none of these have known clinical significance, the higher expression of HDAC7 and HDAC9 enzymes were associated with unfavorable prognosis in pediatric ALL [43], SMARCA2 has important function in the maintenance of HSCs [44], and CD34+ cells from AML patients displayed increased expression levels of CITED2 [45] (Figure 1b).