GCNT1P1, KDM5B/JARID1B (lysine demethylase 5B), SETD2 (H3K36 lysine methyltransferase), MeCP2 (binds methylated CpGs), PHF21A (component of a corepressor complex), miR-3652 and miR-6733 were the epigenetic regulators listed among the 200 genes with the most different expression levels after imatinib treatment in Ph+ ALL cell lines. The gene discussed is PHF21A; the disease is acute lymphoblastic leukemia.