Since we observed that MOC2 tumors were deficient in CD8+ T cells and DCs compared to MOC1 tumors, we evaluated whether IFNB1 expression could induce adaptive antitumor immunity for MOC2 tumor control and whether GM-CSF, a cytokine that stimulates DC functions, could enhance IFNB1-induced tumor control. The gene discussed is CSF2; the disease is neoplasm.