A total of 368 of the variants were present in the gnomAD v4.1.0 joint dataset across populations and mapped to 21 of the 27 genes associated with monogenic PD; here, we list these genes in descending order, based on the number of variants identified in ClinVar: GBA1 (89), PLA2G6 (73), ATP13A2 (27), VPS13C (24), PRKN (23), PSAP (23), PINK1 (19), SYNJ1 (19), MAPT (16), FBXO7 (14), GIGYF2 (9), LRRK2 (7), HTRA2 (6), PARK7 (6), UCHL1 (4), DNAJC6 (3), EIF4G1 (2), ATXN2 (1), CHCHD2 (1), PTPA (1), SNCA (1). (Table S2). The gene discussed is LRRK2; the disease is Parkinson disease.