LRRK2 and atrial fibrillation: The variant NM_198578.4:c.4321C>T (p.Arg1441Cys) in LRRK2 (AF = 0.001) was the most common pathogenic variant with a significant frequency difference in MID comparisons, with a frequency of 0.001, compared to 2.42 × 10−5 worldwide.