Moreover, a manual literature search harbored additional information regarding variants associated with epilepsy, such as rs12713794 in the TPRKB gene and multiple SNPs (rs2979172, rs2921064, rs2979181, rs13270194, rs7823056) in the PRAG1 gene and with epileptic encephalopathy, such as rs59844139 SNP in SLC25A12 and rs10883761 in TRIM8. The gene discussed is TRIM8; the disease is epilepsy.