At least 20 non-type I collagen genes—IFITM5, SERPINF1, CRTAP, P3H1, PPIB, SERPINH1, FKBP10, PLOD2, BMP1, SP7, TMEM38B, WNT1, CREB3L1, TENT5A, MESD, LRP5, KDELR2, CCDC134, SPARC, and MBTPS2—have been implicated in the development of OI [9,10,11,12,13,14,15,16,17,18]. The gene discussed is SERPINF1; the disease is osteogenesis imperfecta.