PPWD1 and esophageal cancer: Exon 11 skipping of CTTN occurred after knockdown of most survival-related SFs (CRNKL1, SNRPB2, PPWD1, RBMX2, and DDX46), while exon 11 inclusion was observed in esophageal cancer in comparison to normal tissue, both in the TCGA database and in our own full-length sequencing data (Figure 7C–E).