Palmitoylation has been shown to activate key signal-transducing proteins in sepsis pathways, such as MYD88, which is essential for toll-like receptor (TLR) signaling upon lipopolysaccharide (LPS) stimulation in bacterial sepsis [17], and STING (stimulator of interferon genes), an immune-regulatory protein [18]. This evidence concerns the gene STING1 and Sepsis.