Parvalbumin-expressing interneurons, which include basket cells, axo-axonic cells, and bistratified cells, are among the most vulnerable in temporal lobe epilepsy (TLE) models, such as the intrahippocampal kainate (KA) mouse model [190], and reduced densities of parvalbumin-expressing and somatostatin-expressing interneurons have been found in a model of early life stress (notably, the maternal separation with early weaning model) [191]. Here, PVALB is linked to temporal lobe epilepsy.