The enrichment of 119 hub genes elucidated the molecular signaling pathways related to atherosclerosis, myocardial infarction, the PI3K-Akt signaling pathway, the HIF1 signaling pathway, the Toll-like receptor signaling pathway, IL-18 signaling and hypertrophic cardiomyopathy and biological processes associated with these hub genes (Figure 2c). The gene discussed is AKT1; the disease is myocardial infarction.