Notably, ErbB, VEGF, TNF, and NF-κB pathways; chemokine signaling; focal adhesion; and leukocyte transendothelial migration associated with PCDs-related genes could explain the specificity of tumor metastasis mechanism in dead patients and further relate to the unfavorable prognosis of BC but with little impacts on patients with good prognosis. This evidence concerns the gene NFKB1 and breast cancer.