The turquoise module was also enriched in response to virus (epithelial cell signaling in helicobacter pylori infection, human papillomavirus infection), central carbon metabolism in cancer, ErbB signaling, VEGF signaling, TNF signaling, Endocytosis, Insulin signaling, NF-κB pathway, chemokine signaling, focal adhesion, leukocyte transendothelial migration, and androgen receptor pathways (Figure 3G). The gene discussed is TNF; the disease is cancer.