MYL3 and hypertrophic cardiomyopathy: Meanwhile, in the hypertrophic cardiomyopathy pathway and adrenergic signaling in cardiomyocyte pathway, which are closely related to the occurrence of hypertrophic cardiomyopathy, myosin Light Chain 2 (Myl2) and myosin Light Chain 3 (Myl3) were the most significant proteins with lactylation (Figure 5D,E).