Moreover, in CD11b+ cells from mice treated with 7aaRGD, genes encoding the following: NEDD4, an E3 ligase involved in the reprogramming of tumor-associated macrophages via CSF1R degradation [39]; CD81, a regulator of the recruitment of NK cells [40]; CD9, a member of the transmembrane 4 superfamily (TM4SF) involved in cell growth, adhesion and motility; the cytokine IL1b and CXCL10, an IFNγ-stimulated chemokine that attracts T cells through binding to its cognate receptor CXCR3, presented increased expression. This evidence concerns the gene NEDD4 and neoplasm.