In support to our hypothesis, qPCR was performed to validate changes in the canonical microglia markers initially identified by RNAseq, and significantly higher levels of Fcrls (and elevated levels of Cx3cr1 and Tmem119) were detected in tumor infiltrating CD11b+ cells sorted from the brains of 7aaRGD-treated mice (Fig. S4E). This evidence concerns the gene CX3CR1 and neoplasm.