ITGAM and neoplasm: However, we cannot exclude the possibility that the downregulation of genes related to antigen processing and presentation pathways in sorted CD11b+ cells from 7aaRGD-treated tumors (bulk RNA-seq data) is due to a higher proportion of homeostatic microglia rather than tumor-activated microglia, which exhibit elevated expression of antigen presentation genes (Fig. S4B-C, E).