For example, glmBoost + Enet [alpha = 0.2] training set (TCGA-LIHC, n = 424) AUC = 0.998; Verification queues (GSE54236, GSE76427, GSE112790; Total n = 526) AUCs = 0.867–0.977 (Fig. 5A–E and Supplementary Material Table 1), which also means that PRGs has a significant pathogenic effect in HCC. The gene discussed is GART; the disease is hepatocellular carcinoma.