IL12RB2 and Anxiety: The finding of altered methylation at the Interleukin 12 Receptor Subunit Beta 2 (IL12RB2) and the Interleukin 12 receptor, beta 2 subunit (IL12RB2) locus is well in line with an involvement of pro-inflammatory cytokines in anxiety in general [57] as well as a recent finding of interleukin-12 in particular to be negatively correlated with cortisol levels in PD patients [58].