Specifically, the effects of ACE on schizophrenia and Alzheimer’s disease were supported by brain cortex and blood eQTLs, the effects of CD40 on schizophrenia were supported by blood pQTLs and brain cortex eQTLs, the effects of NAGA on schizophrenia were supported by blood pQTLs and brain cortex eQTLs, while the effects of DNPH1 on bipolar disorder were supported by blood pQTLs and eQTLs. The gene discussed is CD40; the disease is bipolar disorder.