In addition, Fer-1 withdrawal from GPX4 KO but not control mouse small cell lung cancer (SCLC) cell lines [35] readily induced the release of MIF, and treatment of PMLFs with the GPX4 inhibitor RSL3 equally led to a significant MIF release from ferroptotic cells (Fig. 1I, J). The gene discussed is GPX4; the disease is small cell lung carcinoma.