Interestingly, the percentage L1-specific CD8+ T cells was reduced in VZV-vax + L1165-173 + E744-62 (mean=3.76±2.44) group compared to VZV-vax + L1165-173 alone (Mean=8.65±1.56) suggesting some MHC-I binding competition between these two H-2Db-restricted epitopes in favor of the tumor-specific epitope. Here, CD8A is linked to neoplasm.