In fact, flow cytometry analysis of the cellular lymphoid and myeloid tumor infiltrate showed that IT injection of the L1 minimal peptide epitope with polyI:C led to an increase in activated CD8+ T cells (CD45+CD4-CD8+CD44+CD62L-PD1+) (Fig. 2I, Supplementary Fig. 3A), a non-significant decrease in myeloid cells (CD45+CD11b+)(Fig. 2J, Supplementary Fig. 3B), an increase in neutrophils (CD45+CD11b+Ly6CmidLy6G+)(Fig. 2K) and a decrease in macrophages (CD45+CD11b+Ly6C-Ly6G- F4/80+) (Fig. 2L) compared to saline- and HPV-vax-treated groups. The gene discussed is CD44; the disease is neoplasm.