Luteolin oral administration induced a significant reduction in the number of Ly6G+ neutrophils (Fig. 6N) and Ly6Chi monocytes and immature macrophages (Fig. 6O), and a significant increase of mature Ly6C-MHCII+ and CD206+ macrophages (Fig. 6O, P) during DSS colitis. Here, MRC1 is linked to colitis.