Recent research has suggested that YAP1 may also play a pivotal role in metabolic processes, contributing to the onset of metabolic disorders, such as diabetes‐accelerated atherosclerosis,[43] diabetic kidney disease,[44] and diabetic retinopathy.[45] While several sophisticated molecular mechanisms have been proposed to elucidate the influence of YAP1 activation on the progression of metabolic disorders, the nuclear accumulation of YAP1 stands as a critical step. Here, YAP1 is linked to diabetic retinopathy.