Studies presented that CD8+ T cells typically played an essential role in combating tumors and elevated expression of CD8+ T cells predicted a favorable prognosis in treating patients.[22] Therefore, we utilized TISIDB website to screen the relationship between HIC1 and immune cell infiltrations in a majority of cancers, which emphatically shed light on the correlation between CD8+ T cells and HIC1 in gastric cancer. This evidence concerns the gene CD8A and gastric cancer.