To prevent any off‐target effect of shNEDD4L, NEDD4L‐R, which is resistant to shNEDD4L (TRCN0000000905) targeting, was used to restore NEDD4L expression in NEDD4L‐knockdown colorectal cancer cells, since we did not find in our system that the knockdown efficiency of any published shRNA (different from the 5 shRNAs in the library) was similar to that of shNEDD4L (TRCN0000000905). This evidence concerns the gene NEDD4L and colorectal cancer.