Unlike most solid tumor cells, CML is initiated and maintained by self‐renewing malignant CD34+ stem cells, which exhibit higher oxygen consumption rates (OCRs) than normal CD34+ hematopoietic cells do.[33] Seahorse analysis revealed that, compared to wild‐type K562 cells, PKMYT1‐knockdown cells presented lower OCRs, basal respiration, ATP production, and maximal respiration (Figure 6i‐l). This evidence concerns the gene PKMYT1 and chronic myelogenous leukemia, BCR-ABL1 positive.