TGFB1 and alopecia: These therapeutic functions are linked to underlying pathological processes in AGA and scarring alopecias: BoNT’s inhibition of fibroblast proliferation and TGF-b production may antagonize the DHT-induced upregulation of TGF-b and its subsequent pro-inflammatory signaling, fibrosis, and hair follicle miniaturization in AGA [86,87].