SMC4 and prostate carcinoma: To investigate the contribution of SMC4 to prostate cancer growth and metastasis, we inoculated RM1‐LM‐Vector cells and SMC4 knockdown cells into the tibia of C57BL/6 mice, and 14 days after injection, the mice inoculated with RM1‐LM‐Vector cells showed dramatic increases in bioluminescent imaging (BLI) signals compared with mice inoculated with SMC4 knockdown cells (Figure5A).