The researchers found that P-selectin levels above 40.2 mean fluorescence intensity (MFI) by flow cytometry were significantly associated with a 3-fold-increased risk of non-fatal myocardial infarction, ischemic stroke or transient ischemic attack, and recurrent PAD symptoms (95% CI: 1.3–7, p = 0.009) [49]. Here, SELP is linked to peripheral arterial disease.