Using gene ontology analysis, relevant cancer pathways downregulated after PEMF treatment in HT-1197 cells relative to controls were the tumor microenvironment (TME) pathway (p = 1.49 × 10−41), phosphatidylinositol 3-kinase (PI3K)/AKT pathway (p = 8.63 × 10−43), and cancer drug resistance efflux pathway (p = 4.5 × 10−29). This evidence concerns the gene PIK3CD and cancer.