Similarly, conotoxins that target human Nav1.7, Nav1.8, or α7 nAChR (such as μ-Conotoxin KIIIA [36], μ-Conotoxin MfVIA [37], [Q1G, Delta R14]LvIB [38]) can reduce skin inflammation, improving conditions like acne and eczema, enhancing overall skin health. Here, SCN9A is linked to acne.