Finally, Kim M et al. (2024), in a prospective case-control study, performed a NGS analysis of 24 genes (ASXL1, BCOR, CALR, CEBPA, DNMT3A, ETV6, FLT3, IDH1, IDH2, JAK2, KIT, KMT2D, KRAS, MPL, NPM1, NRAS, RUNX1, SETD2, SF3B1, STAG2, TET2, TP53, U2AF1, and WT1) associated with CHIP variants and cardiovascular diseases [100]. Here, DNMT3A is linked to cardiovascular disorder.