BAG3 and familial dilated cardiomyopathy: While the annual incidence of VA in BAG3 mutation carriers with a DCM phenotype is reported to be only 1.5% [9]—suggesting a lower arrhythmic risk than other genetic causes of DCM such as LMNA or FLNC mutations—this novel BAG3 variant presented with complex VA, preceding the overt DCM phenotype by several years.