While the annual incidence of VA in BAG3 mutation carriers with a DCM phenotype is reported to be only 1.5% [9]—suggesting a lower arrhythmic risk than other genetic causes of DCM such as LMNA or FLNC mutations—this novel BAG3 variant presented with complex VA, preceding the overt DCM phenotype by several years. The gene discussed is LMNA; the disease is familial dilated cardiomyopathy.