PARK7 and Parkinson disease: Other genes, such as PARK7 (DJ-1), Phosphatase and tensin-homolog- (PTEN)-induced kinase 1 (PINK1), and Parkin RBR E3 ubiquitin protein ligase (PRKN), have been implicated in autosomal recessive forms of PD, where mutations in these genes result in the disruption of mitochondrial function and cellular stress responses, contributing to the degeneration of dopaminergic neurons [4,5].